testosterone cypionate injections

The drug is rapidly absorbed after administration. The maximum blood concentration is reached in 25-30 minutes after administration. 40-55% of the active substance is bound to plasma proteins.  Rapidly enters the tissue. It is testosterone cypionate injections metabolized in the liver. The elimination of the drug through the kidneys and extrarenal (through the gastrointestinal tract). The half-life is 40 minutes. Excretion of the drug N kidneys occurs primarily by tubular secretion, and only 1/3 of the drug is released by glomerular filtration. After parenteral administration, 34.8% of the dose of the drug is excreted in the urine in unchanged form.

Indications
Diseases of the peripheral nervous system (neuritis, polyneuritis and polyneuropathy, poliradikulopatii, myasthenia gravis and the myasthenic syndrome of various etiologies); bulbar paralysis and paresis; recovery period of organic lesions of the central nervous system, accompanied by movement disorders; Combination Therapy of demyelinating diseases; intestinal atony.

CONTRAINDICATIONS
Hypersensitivity to any component of the drug, epilepsy, extrapyramidal disease with hyperkinesis, angina pectoris, bradycardia, asthma, ileus, and urinary tract, vestibular disorders, gastric ulcer or duodenal ulcer in the acute stage of pregnancy and lactation, children’s age. Be wary of: gastric ulcer and duodenal ulcer, thyrotoxicosis, diseases of the cardiovascular system, as well as patients with obstructive diseases of the respiratory system, or a history of acute respiratory diseases.

Dosage and administration
subcutaneously or intramuscularly. Dose and duration of treatment is determined individually depending on the severity of the disease.
Diseases of the peripheral nervous system, and myasthenic gravis syndrome, including subcutaneously and intramuscularly 5-15 mg 1-2 times a day. The course of treatment is 1-2 months. If necessary, treatment can be repeated several times with a break between courses of 1-2 months.
To prevent myasthenic crises or severe disorders of neuromuscular conduction is administered 15-30 mg of the solution, and then continue treatment neuromidin  in tablet form, the dose can be increased to 20 -40 mg (1-2 tablets) 5-6 times a day.
Treatment and prevention of intestinal atony: an initial dose – 10-15 mg for 1-2 weeks. The dose can be increased to 30 mg per day.

Side effects
induced excitation of m-cholinergic receptors: salivation, sweating, palpitations, nausea, diarrhea, jaundice, bradycardia, epigastric pain, increased allocation of the bronchi secretion, convulsions. Drooling and bradycardia can be reduced m-holinoblokatorami (atropine, etc.).
Less commonly, after the application of higher doses were observed dizziness, headache, vomiting, weakness, drowsiness, skin and allergic reactions (itching, rash). In these cases, reduce the dose or short-term (1-2 days) interrupt drug. These side effects occur in less than 10% of patients.

Interaction with other drugs
Testosterone cypionate injections enhances the sedative effect in combination with the means oppressive central nervous system. The action and the side effects are enhanced when used together with other cholinesterase inhibitors and nicotinic-M means. In patients with myasthenia increases the risk of cholinergic crisis if applied concurrently with other cholinergic agents. The risk of bradycardia when β-blockers were used prior to the treatment with . The drug can be used in combination with Cerebrolysin. Alcohol increases the side effects of the drug.

Cautions
During treatment should testosterone cypionate injections refrain from driving a car, as well as the classes of potentially hazardous activities that require high concentration and psychomotor speed reactions. Running low dose t3 clen cycle trying to lose bodyfat isn’t a real hot idea imo. women on steroids eurochemlabs steroid side effects in children