Antimicrobial effect due to suppression of the synthesis of bacterial DNA by inhibiting polymerization. It is effective against Gram-negative Mikrosrganizmov sensitive strains that are resistant to antibiotics and sulfonamides. Activity testosterone cypionate vs enanthate against gram-positive bacteria and anaerobes. In the course of treatment may develop microbial resistance.
Concentration in kidney tissue than in the blood. It penetrates the blood-brain and placental barrier into breast milk.
Allergic reactions (skin rash, pruritus, angioedema), nausea, vomiting, diarrhea, gastralgia, testosterone cypionate vs enanthate bleeding from the gastrointestinal tract, cholestasis; drowsiness, headache, blurred vision, and color vision, diplopia, intracranial hypertension, dysphoria, myalgia; renal failure, and an increase in rates of liver enzymes; damage to the articular cartilage and arthralgia in children and adolescents. With prolonged use can: thrombocytopenia, leukopenia, hemolytic anemia, photosensitivity, convulsions. Large doses rarely cause psychotic reactions.
The patient must inform the doctor about the side effects, especially those which are not mentioned in the medical use of the drug instructions.
Overdosing Symptoms: nausea, vomiting, diarrhea, in more severe cases – impaired consciousness, confusion, psychotic reactions, seizures, metabolic acidosis. Treatment: gastric lavage. If the drug has been absorbed and cause severe vomiting, should compensate the loss of fluid and electrolytes; symptomatic treatment.
Interaction with other drugs
should not be administered concurrently with indirect anticoagulants.
May have a depressing effect on the central nervous system (CNS), particularly in the case of simultaneous use of ethanol or other drugs, CNS depressants.
Incompatible with nitrofurans.
If treatment is continued for more than two weeks should monitor renal and hepatic function. During treatment with blacks, Refer a patient to avoid prolonged sun exposure. Purpose nalidixic acid can cause porphyria in patients with this disease. Treatment should be interrupted in case of severe adverse events associated with the central nervous system (increased intracranial pressure, psychotic reactions, convulsions) or allergic reactions (skin rash, photosensitivity). There is evidence of damage to the articular cartilage in children and adolescents. If there are marked arthralgia symptoms, treatment should be interrupted. Patients receiving Negril possible false positive reaction to urinary glucose reducer when the method testosterone cypionate vs enanthate of determining and lozhnovysokie performance 17-keto steroids in urine.
In the period of treatment should refrain from activities potentially hazardous activities that require high concentration and psychomotor speed reactions. super test 400 side effects